Anti Aging Today

Aging - Senescence
Overview, Facts and Insights

 

Aging - Senescence - Overview

Senescence is the state or process of aging. The word senescence is derived from the Latin word senex, meaing "old man" or "old age."

Cellular senescence refers to a phenomena where isolated cells demonstrate a limited ability to divide in culture. Organismal senescence refers to the aging of organisms.

Organismal aging is generally characterized by the declining ability to respond to stress, increasing homeostatic imbalance and increased risk of disease. Because of this, death is the ultimate consequence of aging.

Genetic and environmental interventions are known to affect the life span of model organsims. This gives many hope that human aging can be slowed or changed. Dietary calorie restriction, by 30 percent for example, extends the life span of yeast, worms, flies, mice, and monkeys. Several genes are known to be necessary for this extension, and modification of these genes is also sufficient to produce the same effect as diet.

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Response to Skeptics:

"Man who say it cannot be done should not interrupt man doing it."
- Chinese Proverb

 

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Woody Allen