Anti Aging Today

Anti-Aging Medicine &Therapies

Listed below are links to descriptions of drugs and nutrients which have been proposed as therapies to slow and/or reverse human aging.

The only method proven to slow aging and extend lifespan in mammals is caloric restriction of a nutrient-rich diet, which has been demonstrated to work in rats, mice, and is now being studied in monkeys. While some people practice caloric restriction as a means of extending lifespan, its primary value is as a model to explore how aging can be controlled. Although none of the therapies in this section have been proven to retard aging, there is suggestive scientific evidence that they may have this ability.

Anti-Aging Medicine & Therapies
Table of Contents

0-9
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z

5HTP - Oxitriptan
Oxitriptan or 5-Hydroxy-Tryptophan is the precursor to Serotonin (the brain neurotransmitter linked with pleasure and fulfillment). Oxitriptan is often used in place of L-tryptophan for sleep assistance, depression, and alcohol withdrawal.

Return To Top

Acarbose
Acarbose is used (with diet only or diet and other medications) to treat type 2 (noninsulin- dependent) diabetes (high blood sugar). Acarbose works by slowing the action of certain chemicals that break down food to release glucose (sugar) into your blood. Slowing food digestion helps keep blood glucose from rising very high after meals.

Return To Top

Acetyl-L-Carnitine
A naturally occurring nutrient in the body, acetyl-L-carnitine (ALC) transports fats into the mitochondria. It occurs in many common foods, including milk. Studies have shown that ALC may help protect the brain by nourishing NMDA-sensitive glutamate receptors, which normally decline with age. ALC has also been shown to help prevent the formation of lipofuscin, a potassium age pigment, and to increase cerebral blood flow.

Return To Top

Adrafinil
Adrafinil acts to stimulate brain activity only when stimulation is required. Modafinil is the latest, more potent analogue of Adrafinil. Both drugs act on brain Alpha 1 post synaptic receptors and make them more susceptible to norepinephrine, thus increasing alertness and concentration. They do not appear to affect other brain functions.

Return To Top

Alpha-Lipoic Acid
Alpha-Lipoic Acid, also known as lipoic acid, is a highly potent antioxidant that counteracts reactive free radicals in the mitochondria, the power plants of cells where energy for all cellular activities is generated. Some scientists believe that mitochondrial free radicals play an important role in human aging, and have theorized that extra amounts of free-radical inhibiting compounds such as alpha lipoic acid may be able to slow aging. Alpha-Lipoic Acid is also effective in recycling other antioxidants such as Vitamin E back into their original form after they detoxify free radicals. There also is evidence that alpha lipoic acid can reduce glycation damage due to excess glucose in the blood, which may be involved in aging, and that it can improve patients with diabetes, which has been described as an accelerated form of aging.

Return To Top

Aminoguanidine
Aminoguanidine may have the potential to slow the aging process by protecting the proteins that make up the human body. Proteins such as the skin proteins (collagen and elastin), eye lens protein, nerve protein and kidney proteins. All the body's proteins deteriorate with advancing age and more so in diabetes (diabetics have 2-3 times the number of cross-linked proteins when compared to non-diabetics and this has lead credence to the fact that diabetes can be viewed as a form of accelerated aging).

Return To Top

Aniracetam
Aniracetam acts on the central nervous system (CNS), stimulating the learning process and the memory. Pharmacological studies have shown that Aniracetam stimulates the functions of certain neuronal receptors by means of glutamic acid, bringing about memorization processes (AMPA receptors) and protection of nerve cells (metabotrophic receptors). Clinical studies have shown specific therapeutic activity in elderly patients affected by alterations of the cognitive functions. Both long and short term memory improvement have seen in addition to learning, attention span, alertness, concentration, reasoning and absent mindedness.

Return To Top

ATP - Adenosine Triphosphoric Acid
Organic compound composed of adenine, the sugar ribose, and three phosphate groups. ATP serves as the major energy source within the cell to drive a number of biological processes such as photosynthesis, muscle contraction, and the synthesis of proteins.

Return To Top

Calorie Restriction
Since the 1930's it has been known that a diet restricted in calories, but otherwise rich in nutrients, dramatically extends the life span of experimental animals. Over two thousand studies have confirmed the effectiveness of caloric restriction.

Return To Top

Carnosine
Carnosine supplements have been popular among bodybuilders and athletes mainly for improving muscular fatigue. Now, based on over 800 studies, it's being viewed as one of the most important supplements for longevity based on its amazing properties. It is also a neuroprotectant, a modulator of enzyme activities, and a chelator of toxic metals.

Return To Top

Centrophenoxine
Centrophenoxine removes lipofuscin, potassium age pigment from the brain, heart and skin. Appearances of lipofuscin in the skin are referred to as liver, or age spots. Lipofuscin occurs in much higher levels in Alzheimer's patients than in their counterparts, and some theories relate brain and memory function to the ability of potassium to enter and exit brain cells. As we age, this ability is reduced and potassium levels rise. Centrophenoxine can also increase production of brain RNA and aid in a patient's oxygen consumption and carbon dioxide production.

Return To Top

Chelation Therapy
Chelation therapy is used in patients with heavy metal toxicity. An intravenous (IV) synthetic amino acid (EDTA) is used to isolate (chelate) heavy metals such as iron and lead, removing them from the bloodstream and tissues. Many believe chelation therapy, along with a proper nutritional program, aids in the breakdown of the plaques that line the arteries and cause arteriosclerosis. The end result of this type of treatment in some people is increased blood flow and a marked decrease of excessive deposits of plaques in arteries and organs such as the liver, kidneys, heart and brain.

Return To Top

Chromium Picolinate
Chromium picolinate is a nutritional supplement that works to increase the efficiency of insulin to optimal levels.  Gaining increased popularity in the United States, this supplement has been touted a miracle mineral, one advertised to have myriad effects including weight loss, mood enhancement, energy promotion, increase in life span, and even the prevention of acne (Krzanowski, 1996).

Return To Top

Coenzyme Q10
Co-enzyme Q-10, or ubiquinone, may improve the functioning of the immune system, increase the body's resistance to stresses, including bacteria and viruses, and improve the condition of cardiac patients. Co-enzyme Q-10's major function in the body is its action as a co-factor in the production of ATP in the mitochondria. Studies have shown that many patients with heart conditions had lower levels of Co-enzyme Q-10 than their healthy counterparts, and that increasing the levels improved the patient's condition and mental outlook. Co-enzyme Q-10 may also stimulate the immune system to protect against carcinogens.

Return To Top

Conjunctisan A
A product specifically designed to treat aging eye disorders such as cataracts, Conjunctisan A contains natural lysates, which purport to improve eye conditions by stimulating the natural healing and repair processes. Regular, longer use of conjunctisan A may improve eyesight in cataract sufferers, as well as myopia.

Return To Top

Cysteine
Cysteine is a sulfur containing non-essential amino acid and is closely related to cystine, as cystine consists of two cysteine molecules joined together. It is an unstable nutrient and easily converts to cystine, but this does not cause a problem, since both can convert into the other – as required by the body.

Return To Top

Deprenyl
Deprenyl is a drug that has been widely used to treat Parkinson's disease. In Parkinson's disease, dopamine, a major nerve transmitter, decreases due to the action of two enzymes, nonoamine oxidases (MAOS). MAO B occurs in the brain; MAO A occurs outside the brain and breaks up some amino acids present in food, thus serving a necessary purpose. Deprenyl inhibits only MAO B, and thus in combination with L-Dopa may be used to treat Parkinson's. Deprenyl may also act against several toxic chemicals produced when MAO B destroys dopamine and may act as an antidepressant.

Return To Top

Dilantin (Phenytoin)
In 1980, Russian scientists reported that the drugs Dilantin (phenytoin) and Phenformin had extended animal lifespan by 25% and 23% respectively in a strain of mice prone to autoimmune disease. Dilantin is an FDA-approved drug commonly prescribed to normalize electrical activity in epilepsy patients. Studies around the world have shown that Dilantin is useful for a wide variety of conditions including depression, headache, and neurologic disorders. Phenformin is a prescription antidiabetic drug, which lowers blood sugar in patients suffering from this disease, which suggests that it might have antiglycosylation effects. Both drugs have serious side effects, which makes them relatively poor candidates for long-term use.

Return To Top

DHEA (Dehydroepiandrosterone)
Originally marketed as a weight loss supplement, DHEA is now promoted as being beneficial for treating a wide variety of medical conditions, including cancer, heart disease, Alzheimer's, and AIDS. It is also purported to have anti-aging qualities. Studies in rodents and test tubes have shown daily doses of DHEA can prevent or benefit such conditions as cancer, heart disease, osteoporosis, diabetes, lupus, obesity, and viral infections.

Return To Top

DMAE (Dimethylaminoethanol)
DMAE (Dimethylaminoethanol) is a chemical naturally produced in the human brain. It is thought to be used by the body in converting the precursor choline to the neurotransmitter, acetylcholine. This is the basis for the reasoning behind the theory that supplementing with DMAE will enhance brain activity.

Return To Top

Estrogen
Estrogen is the female sex hormone. Before menopause, the ovaries produce estrogen. Low levels of estrogen have been linked to osteoporosis, arteriosclerosis, declining cognitive function and increased risk for Alzheimer's disease. Estrogen replacement therapy has been shown to decrease incidences of osteoporosis and arteriosclerosis, improve cognitive function and increase life span.

Return To Top

GH3
(see Procaine)

Return To Top

Ginkgo
Ginkgo, derived from the leaves of the ginkgo tree, stimulates brain activity by increasing levels of dopamine and improves the flow of blood to the brain and all other organs by dilating, or relaxing the arteries and veins. Rich in flavonoids, antioxidants that protect the body against free radicals, ginkgo has also been shown to prevent blood clots by inhibiting blood cells from sticking together.

Ginkgo has been used in Oriental medicine for thousands of years. European researchers have recognized its properties since the 1970s and today ginkgo is widely prescribed in Europe for maladies ranging from headaches to hemorrhoids. Studies have shown ginkgo may have significant anti-aging benefits: improving mental performance and circulation, as well as inhibiting free radicals, thus preventing heart disease, cancer and arthritis.

Side Effects and Contraindications: There are no known side effects, or contraindications.

Distribution: Ginkgo is available without a prescription in natural food stores and most drug stores. The recommended dosage is one 60mg capsule, or tablet, three times daily, as the effects only last a few hours at a time.

Gingko may soon be available by prescription in the United States. Harvard chemists are testing ginkgo as a potential drug for asthma sufferers and to help prevent the rejection of transplanted organs.

Return To Top

Ginseng
For 5000 years, the Chinese have revered this herb as a cure-all and antidote to the ravages of aging. Ginseng is primarily a stimulant and some researchers speculate that it may indirectly stimulate the production of stress hormones that can increase stamina. Ginseng also contains choline, a chemical found in the brain that is essential for learning and memory retention. Studies have found that people taking ginseng make fewer mistakes and complete tasks more quickly than those who do not.

According to studies performed by Soviet scientist L.I. Brekhman, Ph.D., ginseng helps the body to cope better with stress by acting as an adaptogen, regulating and normalizing blood sugar and blood pressure levels.

Researchers at Japan's Kanazawa University found that compounds called unpurified saponins found in ginseng inhibited the growth of cancer cells and even converted diseased cells into normal cells. In addition, ginseng contains antioxidants, known to prevent cellular damage due to free radicals.

Other anti-aging benefits of ginseng are that it helps to raise levels of beneficial high-density lipoprotein or "good" cholesterol. In addition, ginseng may help to control some of the side effects of menopause, such as hot flashes.

Distribution: Ginseng, preferably the American, or Siberian varieties, is available in natural food and drug stores, and comes in many forms including capsules, tea and powder. Always take ginseng one hour before eating. In capsule form, take one up to three times daily. For tea, drink one cup daily. If you use powder, mix 5 to 10g in liquid daily. Avoid the Chinese panax variety as it may be too strong.

Side Effects and Contraindications: As ginseng has a mildly estrogenic effect on the body, in rare cases it may cause vaginal bleeding in post menopausal women. People with high blood pressure, or irregular heartbeat, should not take ginseng.

Excessive use may make some people very jittery. Be careful not to exceed the recommended dosages. As vitamin C can interfere with the absorption of ginseng, wait two hours before or after taking ginseng to take vitamin C.

Return To Top

HGH - Human Growth Hormone
Human Growth Hormone (hGH) is secreted by the pituitary gland. It causes growth and repair of body tissues, including the muscles, the skin, the kidneys, and more. HGH levels naturally rise sharply throughout puberty, peak at about age 20, and then slowly decrease. HGH has been used to treat children who fail to make sufficient growth hormone and to treat adults with hGH deficiency.

Return To Top

Homocysteine
It has become evident during the past few years that homocysteine (Hcy), a sulfur-containing amino acid involved in methionine metabolism, is a major independent risk factor for cardiovascular disease-is joining the ranks of dyslipidemia, hypertension and smoking. Interestingly, it was recognized more than 30 years ago that individuals with an inborn error of metabolism, cystathionine betasynthase deficiency, had a 50 to -100 fold elevation in circulating Hcy and excreted large amounts of Hcy in the urine. Premature vascular disease and implicated subclinical deficiencies of B-vitamins are contributing factors. It was estimated that a 5 umol/L increase in serum Hcy is associated with 60 to 80 percent increased risk of coronary artery disease (CAD).

Return To Top

Hydergine
An important anti-aging and nootropic drug, hydergine may help protect the brain from free radical damage and oxygen starvation. Hydergine maintains the brain's optimal metabolism of oxygen. Oxygen is a free radical scavenger and generator. Free radicals cause age-associated damage, and at optimal levels, oxygen will neutralize more free radicals than it generates. Hydergine may also stimulate the growth of dendrite nerve fibers, which may have a possible link to intelligence. Also, recent studies suggest that hydergine may reduce Senescent Cell Antigen (SCA), a destructive auto-antibody appearing more frequently in elderly cells. SCA damages cells and finally destroys them.

Return To Top

Idebenone
Idebenone is an analogue of Coenzyme Q10. In most respects, Idebenone shares its traits with Coenzyme Q10. Like Coenzyme Q10 is might be useful for aging. It differs from it in some important ways, which may make it more useful. Under certain circumstances, Coenzyme Q10 (CoQ10) may become a pro-oxidant. These circumstances are conditions in which hypoxia or lack of oxygen occurs. In cases of shock, heart attack, stroke, or poor circulation, CoQ10 auto-oxidizes and unleashes massive amounts of various free radicals that damage delicate tissues and because CoQ10 is necessary for electron transport and ATP (chemical energy) production, cellular death may ensue. Idebenone, on the other hand, suppresses free radicals and continues ATP production in hypoxic situations. This may make it a useful supplement for individuals at risk for those conditions.

Return To Top

Intravenous Vitamins and Minerals
You are what you absorb. The body's ability to absorb nutrients can be inhibited by many factors, including previous medicine and antibiotic use, yeast, or bacterial overgrowth, as well as prevailing nutritional deficiencies. To ensure absorption of nutrients, intravenous vitamins and minerals are given. By receiving the necessary nutrients intravenously, a person's body is able to utilize them and receive their benefits immediately. Intravenous vitamins and minerals have been used in treatment of various chronic conditions, including cancer, fatigue and immune dysfunction.

Return To Top

KH3
(see Procaine)

Return To Top

Levodopa (L-Dopa)
In 1977, George Cotzias, et al. reported a 50% increase in the mean lifespan of rats fed very high doses of L-Dopa, the precursor to the neurotransmitter dopamine. In another study in rats, it was shown that the incidence of movement disorders among aged rats were almost totally reversed by L-Dopa, which enabled the rats to swim almost as well as young rats. L-Dopa is used to treat Parkinson's disease patients, with major improvements usually occurring for several years followed by a steep decline in function coupled with adverse side effects. The problem with L-Dopa as an antiaging drug is its side effects at high doses, which include abnormal heart rhythms, movement disorders, mental disturbances, and a greater risk of at least one type of cancer.

Return To Top

Lycopene
A member (along with beta-carotene) of a family of plant pigments called carotenoids. There are more than 600 different carotenoids, but lycopene and the carotenes are the most important ones. They are the pigments that give leaves, tomatoes and other plants their bright colors. Lycopene is the best antiaging candidate of this class of compounds because it is the most efficient quencher of an especially dangerous free radical called singlet oxygen.

Return To Top

Magnesium
Magnesium helps prevent osteoporosis, protects against heart disease, lowers blood pressure and acts as an antioxidant. The mineral also may help prevent diabetes and can ease symptoms of premenstrual syndrome.

Distribution: People who do not regularly eat magnesium-rich foods (such as whole grains, nuts, seeds and legumes) should probably take a 200mg to 300mg supplement each day. Multi-vitamins typically contain only 100mg of the mineral, so additional magnesium supplementation may be necessary.

Side Effects and Contraindications: Magnesium oxide should be avoided in most cases, as most people do not tolerate it well. Better choices for magnesium supplementation are magnesium chloride, magnesium Aspartate, magnesium gluconate and magnesium lactate.

More than 600mg to 700mg of magnesium daily can cause diarrhea. Most people can tolerate as much as 500mg of magnesium daily, if they have normal kidney function.

Anyone with kidney problems, heart failure, or a history of heart attacks, should consult a physician before considering magnesium supplements.

Return To Top

Melatonin
Melatonin, a hormone made by the pineal gland, affects many organs, including the thymus, the pituitary and the hypothalamus. Melatonin plays a major role in setting the internal clock. Blind people use melatonin to improve their ability to sleep and to regulate their circadian cycle. It is also used to combat jet lag. Studies on mice suggest that melatonin may play an important role in increasing life span.

Return To Top

Metformin
Metformin may improve insulin use and help prevent age-related onset diabetes. It may increase the sensitivity of peripheral tissues (like muscles) to the effects of insulin, restoring the effects of glucose and insulin to younger physiological levels. Metformin may also be a useful dieting aid as it acts to stabilize sugar levels, thus preventing sugar highs and lows and sugar cravings.

Metformin's anti-aging benefits may also include decreasing risk of age-related adult-onset diabetes, prevention of sugar cravings, improved body composition with improved insulin use, stabilization of sugar levels and slowing of the effects of diabetes.

Pharmacology: Synonyms: La-6023 (Metformin) Chemical Name: 1,1 Dimethylbiguanide hydrochloride: Molecular Formula: C(4)H(11)N(5),HCL Molecular Weight: 165.6 CAS Registry: 657-24-9 (Metformin):1115-70-4 (Metformin HCL).

Side Effects and Contraindications: Side effects in healthy aging individuals are rare, but may include nausea, loss of appetite, and very rarely, vomiting, stomach pain and diarrhea. Patients with diabetes type I and II sometimes take doses as high as 3 grams a day, in which case side effects may include hypoglycemia, or lactic acidosis.

Use of Metformin is contraindicated when combined with Thiazide, Cimetidine, diuretics, or other anti-hypertensive products, which could cause renal malfunctioning. Also contraindicated in individuals with ketonuria, serious hepatic and renal disorders, serious cardiovascular problems, serious respiratory problems, suprarenal insufficiency, chronic alcoholism, serious dystrophic illness, acute hemorrhaging, gangrene, diabetes with previous episodes of lactic acidosis, or hypersensitivity to Metformin.

Distribution: Metformin is supplied in 250mg, 500mg, and 850mg tablets under the trade names Devian TM , Dextin, Diaberit TM, Diabetex, Diabetosan, Diabex, Diaformin, Glucamet, Glucophage, Glucophate S, Mediabet, Mesorit, Metforal, Metiguanide and Orabet.

Note: Because metformin may cause the malabsorption of vitamin B12, patients should supplement their diets liberally with vitamin B12.

Return To Top

NADH (Nicotinamide Adenine Dinucleotide)
Nicotinamide adenine dinucleotide, or NADH, is a coenzyme made from vitamin B2, or niacin. It’s present in all living cells. As a coenzyme, NADH serves an important role in helping enzymes to function as they should. (An enzyme is a protein that works like a catalyst in the body to prompt chemical changes in other substances; breaking down food into energy is an example.)

Return To Top

Oxitriptan
(see 5HTP)

Return To Top

Pantothenic Acid
(see Vitamin B5)

Return To Top

Phenformin (see Dilantin)

Return To Top

Phenytoin (see Dilantin)

Return To Top

Picamilon
Sometimes also spelled Pikamilon or Pikamilone, this is a Russian developed nootropic. It is in essence Niacin (vitamin B3) bonded to GABA. Studies have shown that it rapidly crosses the blood-brain barrier, however its effects are much greater and broader than just taking a GABA and Niacin supplement.

Return To Top

Piracetam
The world's best-selling nootropic drug, Piracetam, is purported to prevent and correct memory loss due to old age, sharpening memory and improving clarity and attention to detail. It is used to treat senile dementia and Down's syndrome. A derivative of the amino acid GABA, Piracetam helps to restore levels of the neurotransmitter Acetylcholine. It also increases the sensitivity of muscuarinic receptors, which decreases with age. It brings about important metabolic modifications in nerve cells, which results in greater receptiveness and increased use of chemical energy by these cells.

Return To Top

Pregnenolone
Produced in the mitochondria throughout the body from cholesterol, pregnenolone is the base material of all human steroid manufacture, including DHEA, progesterone, testosterone and estrogen. It appears to block the effects of cortisol, preventing stress. Pregnenolone stimulates brain NMDA receptors. These receptors, which decline with age, play an important role in the function of synapses and neurons, influencing learning and memory. Pregnenolone levels are directly correlated with cognitive ability. Pregnenolone levels decline with age.

Return To Top

Procaine (GH3 And KH3)
The first drug suggested for use in reversing aging in modern times, Romanian physician Dr. Anna Aslan suggested in 1956 that procaine could be used to combat arthritis, arteriosclerosis, senile skin changes and baldness. Procaine containing benzoic acid has been shown to markedly improve the absorption of procaine by fats, thus quickening its absorption by the human body. Procaine also increases the speed with which the nerves conduct impulses, and decreases the rate of excretion of the 17 kerosteroids, which usually increases with age.

Return To Top

Procysteine
(see Cysteine)

Return To Top

Prolotherapy
"The rehabilitation of, and incompetent structures such as a ligament, or a tendon, by the induced proliferation of new cells" (Webster's New International Dictionary). A ligament is a band of fibrous tissue that holds bones together. Just like a rubber band, a ligament can become "overstretched". The resulting laxity can cause severe pain as bones rub together, or muscles are overworked as they tighten in an attempt to stabilize the bones. Prolotherapy is a treatment where a proliferate solution of natural substances is injected directly into the site where the weakened ligament attaches to the bone. Injections trigger the body's own immune system to grow new and healthy tissue, which then properly stabilizes the bones and joints, relieving musculoskeletal pain and stiffness. Prolotherapy is one of the treatments of choice for chronic pain.

Return To Top

Pyridoxine
(see Vitamin B6)

Return To Top

Pyritinol
Recent evidence suggests that a European medication called Pyritinol may be an effective treatment for Alzheimer's disease. When compared Hydergine and placebo, Pyritinol produced continuous improvement in cognitive function, which was more pronounced than in the Hydergine group. Pyritinol is used in Europe for the treatment of a wide variety of neurologic disorders.

Return To Top

RN 13
RN13 is designed specifically to treat premature aging and geriatric complaints. It acts on cell respiration and metabolism in organs which are particularly affected by aging. RN13 contains 13 different animal source RNAs, as well as vitamins, amino acids, procaine and glutamic acid and biolecithin to improve cerebral activity. In the body, RNAs are responsible for protein biosynthesis help repair and regenerate body tissues and organs, and RN13 purports to work on the principle that animal source RNAs from specific organs may stimulate the same organs in humans. RN13 has been shown to make aging individuals more alert and vital and to improve weak concentration, defective memory, anxiety, troubled sleep and lack of appetite.

RN13's anti-aging benefits may include prevention and treatment of premature aging and all types of age-related disorders, lifting of apathy and potential increase in life span.

Pharmacology: A multi-combination product, of which each liquid capsule contains macromolecular organ substances out of embryo 0.37ng, placenta 0.1ng. amnion 6-pg, funiculus umbilical 60pg, cor 0.2ng, pancreas 0.1ng, mucosa intest 0.1ng, glandular suprarenal 0.1ng, glandular parathyroid 20pg, testes juv. And fet. 0.2ng; as well as a mixture of the following drug additives; heparin 5x10-3IU, L-glutamic acid 10ug, methenolone acetate 4ng, trijod thyroxin HCL 4pg, vitamin E 40ng, vitamin B12 40ng, vitamin B6 40ng, p-amino benzoyldiethylaminoethanol HCL (Procaine) 8ng, biolecithin 10mg, trace elements (Fe, Co, Cu, Mg, Zn, Ca) 1.5ng, sodium dodecyl sulfate 15ug, medium chained triglyceride 410mg.

Side Effects and Contraindications: Side effects are rare, but may include mild irritation at the site of an injection and minor allergic reactions such as a skin rash. People suffering disturbances in purine metabolism, such as gout, should avoid RN13 therapy. Antibiotics and drugs that suppress the immune system may inhibit RN13's efficacy.

Distribution: In severe cases, RN13 is administered by injection and supplemented by ampules, or capsules. In less severe cases, 2ml ampules and 0.5ml liquid capsules are available. VitOrgan of Germany manufactures RN13 under the trade name NeyGeront.

Notes: A useful long-term supplement and designer treatment aimed directly at improving the aged condition.

Return To Top

Selenium
There has never been a study to test the effects on lifespan of the trace mineral selenium, but an early study, which examined the toxicity of selenium (and other minerals) found, by accident, that it extended the lifespan of laboratory mice. There have been dozens of studies showing that dietary selenium can help to prevent a wide variety of cancers, and that it may be useful in the treatment of cancer. Anyone taking selenium on a daily basis for antiaging purpose should be careful to keep their doses low to avoid the possibility of toxic side effects.

Return To Top

Sodium Oxybate (SO)
Sodium Oxybate (SO) is one of the controversial anti-aging drugs available today. Normally referred to as GHB, its effects (as well as its reputation) are varied and wide. SO has developed a rather difficult reputation as a drug of abuse. Low to medium doses have been used to treat alcohol withdrawal and as a mild general anesthetic. Medium doses may act as a relaxant. At high doses, SO may be a potent stimulator of human growth hormone, as well as a very powerful sleep agent. It has been noted to double concentrations of dopamine in the brain and appears to inhibit the release of dopamine from nerve endings without preventing the manufacture of dopamine. Although it has not been sufficiently studied clinically, SO is reported to have a significant effect on the libido in both men and women.

SO's anti-aging benefits may include reduced fat levels, improved muscle mass and condition, deep REM sleep, treatment of insomnia and narcolepsy, improved libido and sexual performance and the ability to act as a general relaxant and soothing agent.

Pharmacology: Sodium Gamma-hydroxybutyrate Wy-3478. Chemical Name: Sodium 4-hydroxybutyrate Wy-3478. Chemical Name: Sodium 4-hydroxybutyrate. Molecular Formula: C(4)(H)NaO(3) Molecular Weight: 126.1 CAS Registry: 502-85-2. Also known as GHB.

Side Effects and Contraindications: Side effects may include sudden sleep, dizziness, nausea, vomiting and headaches. At higher doses, side effects may include a moderate slowing of the heart, small changes in blood pressure and cardiac and respiratory depression and also, in a few cases, muscle spasms, or twitches as the patient enters SO-induced sleep. Patients suffering from Cushing's disease, convulsions, bradycardia, severe cardiovascular problems, severe hypertension, hyperprolactinemia, epilepsy, narcotic drug dependence, individual hypersensitivity, or who are using depressants, should avoid SO. It should not be used with alcohol.

Distribution: SO is available in liquid form in vials of 10ml, 50mg, 100mg, 30ml and 140ml under the trade names Alcover, Gamma-oh and Somsanit.

Notes: It would be highly advisable to ensure that the patient informs his/her partner about the usage of SO. This will ensure that s/he does not become frightened, if the patient either undergoes muscle spasms/twitches before going into a deep sleep, a sleep from which s/he is unlikely to be aroused for 2 to 4 hours. Unfortunately SO has received a lot of bad press. This is likely due to people using the product in an incorrect manner and under the wrong circumstances. Furthermore, there is concern that since SO is a "desired" product, underground chemical factories are producing impure, adulterated GHB (a situation which would be dangerous for any substance destined for human consumption).

Return To Top

Synthetic Antioxidants
In the 1950s and 60s, Denham Harman of the University of Nebraska Medical Center, the originator of the free radical theory of aging, conducted a series of experiments in which he extended the mean lifespan of short-lived mice with various synthetic antioxidants up to 61%.

Return To Top

Testosterone
Although the decline in testosterone production as men age (sometimes referred to as "andropause") is not as dramatic as the drop in women's estrogen production with the onset of menopause, testosterone decline is a serious issue for many older men. Among other problems, declining testosterone production is strongly associated with impotency and libido problems.

Return To Top

Thym-Uvocal
Thym-Uvocal contains a standardized combination of thymus peptides, which may, in a natural manner, replace the decrease of thymic secretion associated with increasing age. The thymus gland undergoes an age related decrease in production of its various peptides. As thymus factors have been correlated with the strength of the immune system, Thym-Uvocal may help increase the strength of the immune system. It appears to have a favorable action on the T-4 cell ratio, and thus a stimulating and modulating action on the cellular immune system. Thym-Uvocal increases levels of antibodies and phacytosis, increases interleukin-1 production, and activates macrophages and enhances their cell destruction action.

Thym-Uvocal's anti-aging benefits may include improved strength of immune system, an increase in the thymic peptide blood count, prevention and treatment of infection, treatment of cancer, treatment of rheumatic disease, treatment of dermatology disorders such as neurodermatitis, aphtosis and psoriasis, treatment of skin allergic reaction and states of exhaustion, and management of AIDS.

Pharmacology: Contains protein-free dry substances from calf thymus extract.

Side Effects and Contraindications: There is a possibility of allergic minor reactions. Thym-Uvocal should be administered to patients with thymic hyperfunction, such as myasthenia gravis, thymic tumors and hypothyroidism.

Distribution: Thym-Uvocal is available in 2ml ampules, topical cream and 240mg tablets. Mull of Germany manufactures it.

Notes: The elderly are the most important target group for the administration of Thym-Uvocal and Thym-Uvocal's main indications are disease of old age.

Return To Top

Thymic Protein
Thymic proteins are produced by the thymus gland, which plays an important role in the immune system. Thymic proteins program T-lymphocytes, the "shock troops" of the immune system. T-4 (helper) cells are central to the functioning of the immune system, and are activated by a certain thymic protein. This protein has been reported to strengthen the immune system, fight viral infections, and stimulate the bone marrow to produce more white and red blood cells, and fights against future illness.

Thymic protein's anti-aging benefits may include an increase in total white blood cell count, increased T-4 and T-8 levels, increase in total red blood cells and an increased potential life span.

Side Effects and Contraindications: This thymic protein should be avoided in patients taking large doses of steroid hormones.

Distribution: The standard dosage for healthy people is 2 micrograms per day.

Return To Top

Trimethylglycine
Trimethylglycine is a methyl donor supplement that assists in methylation and may help protect cellular DNA from mutation. As humans age, methyl groups can decrease. Mildly elevated levels of homocysteine, an amino acid, have been found in 21 percent of patients with coronary artery disease and 24 percent of patients with cerebrovascular disease. Trimethylglycine aids in the conversion of homocysteine to methionine.

Distribution: Trimethylglycine is available in powdered form from Klabin Marketing.

Return To Top

Vasopressin
One of the most potent nootropic drugs, vasopressin, is a hormone secreted by the posterior portion of the pituitary gland. While it may help prevent frequent urination, vasopressin's main use is to treat memory deficits due to old age, senile dementia, drug toxicity and amnesia. Whenever a memory is deposited in the brain, vasopressin regulates the process. It helps select bits of information from the stream of consciousness and forms this information into an image, or concept, which is eventually transformed from an electrochemical impulse into a chemically encoded long-term memory. Vasopressin's benefits may include enhanced clarity, increased attention to detail, improved short-term memory and improved memory imprinting (when taken before an event, one can recall the event later in much greater detail). Vasopressin is so powerful that it has been banned in some California colleges for giving students an "unfair" advantage.

Vasopressin's anti-aging benefits may include treatment and prevention of age-related mental decline, prevention and treatment of senile dementia, improved short-term memory, attention and clarity, enhanced memory imprinting, and treatment of diabetes insidious.

Pharmacology: Synonyms: L-8; Lipressina: LVP. Chemical Name: (8 lysine) Vasopressin; Cys-Try-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH(2) cyclic (1->6) disulphide. Molecular Formula: C(46)H(65)N(13)O(12)S(2) Molecular Weight: 1056.2 CAS Registry: 50-57-7 (Vasopressin is normally Lypressin, a synthetic hormone, or extracted from pigs' pituitary glands. The other hormone Pitressin, or Argipressin, which is extracted from all other mammals, including man.

Side Effects and Contraindications: Side effects include rhinorrhoea and nasal itchiness, headaches, conjunctivitis, sore throat, nausea, abdominal pain and the urgent need to defecate as a result of increased peristalsis. Vasopressin is contraindicated for patients suffering from coronary insufficiency, or using halothane, or cyclopropane anesthetics. It should be administered with caution in cases of hypertension, epilepsy, advanced arteriosclerosis, or any case where increased blood pressure is to be avoided.

Distribution: Vasopressin is available in 5ml, or 12ml nasal sprays under the trade names Diaped Lypressin Injection BP 1993, Lypressin Nasal Solution USP 23, Neo-Lidocaton TM, Postacton, Postacton TM, Syntopressin, Vasopresina, Vasopressin, Vasopressin TM, Vasopressine, and Vasopressine TM.

Notes: Vasopressin is a commonly used nootropin. For general anti-aging purposes, it is recommended that it only be used when required and that it is avoided by anyone suffering from a cardiovascular problem.

Return To Top

Vinpocetine
Vinpocetine improves brain energy and blood supply and has been used as a preventative and as a treatment for stroke and other brain injury. It acts as a cerebral metabolic activator, which may improve cerebral circulation and enhance oxygen and glucose utilization in the brain. Vinpocetine may diminish, or reduce, disturbances due to hypoxia, or to deficient cerebral metabolism. It has been noted to improve oxygen and glucose utilization by brain cells and increase their resistance to damage by hypoxia.

Return To Top

Vitamin B5 (Pantothenic Acid)
Pantothenic acid (PA), a B-complex vitamin, is essential for humans and animals for growth, reproduction, and normal physiological functions. It is a precursor of the coenzymes, CoA and acyl carrier protein of fatty acid synthase, which are involved in more than 100 different metabolic pathways including energy metabolism of carbohydrates, proteins and lipids, and the synthesis of lipids, neurotransmitters, steroid hormones, porphyrins and hemoglobin.

Return To Top

Vitamin B6 (Pyridoxine)
Vitamin B6, also known as pyridoxine is part of the B group vitamins and is water-soluble and is required for both mental and physical health.

Return To Top

Vitamin E
The major fat-soluble compound that protects our cell membranes against oxidative damage. It can break the self-perpetuating chain of oxidative reactions in unsaturated fatty acids in membranes. Vitamin E also helps maintain the antioxidant activity of selenium, and works with this trace mineral to help boost immune function. There have been highly persuasive studies in humans showing that regular vitamin E intake can reduce the risk of heart attacks in both men and women, and that it can protect us from several types of cancer.

Return To Top

Yohimbine
Yohimbine is a pharmaceutical preparation derived from the bark of a tree, called the Corynanthe Yohimbine, which has been useful in the treatment of impotence. Yohimbine acts upon the alpha 2 adrenergic nerve cells and blocks their receptiveness to neurotramsmitter activity. It is theorized that inhibition of these cells increases the blood flow through the penis, while at the same time reducing the flow of blood from the penis. Furthermore, Yohimbine increases blood levels of the neurotramsmitter norepinephrine, one of the body's own prosexual chemicals affecting the hypothalamus. Yomhimbine may also increase levels of acetylcholine, a neurotransmitter that has an effect on male erection response.

The anti-aging benefits of Yohimbine are purported to be the improvement of strength, duration and response of male erection, libido enhancement and improved sexual performance.

Pharmacology: Synonyms: Aphrodine Hydrochloride: Chlorhydrate de Quebrachin; Corynine Hydrochloride. Chemical Name: Methyl 17alpha hydroxy-yohimban-16alphacarboxylate hydrochloride. Molecular Formula: C(21)H(26)N(2)O(3), HCL Molecular Weight: 390.9 CAS Registry: 146-48-5 (Yohimbine); 65-19-0 (Yohimbine hydrochloride).

Side Effects and Contraindications: Yohimbine is likely to be more sensitive in the elderly, where it can lead to over stimulation to the point of nervousness and anxiety. Other side effects may include nausea, vomiting, increased blood pressure, tremors, dizziness and headaches. Patients with inflammatory disease of the urogenital tract, known or suspected prostate or mammary cancer, hypercalciuria, ischemic heart disease, untreated congestive heart failure, glaucoma, extrapyramidal disorders and hyperexcitable states should avoid Yohimbine.

Distribution: Yohimbe is available in 1mg, 2.5mg, 5mg and 10mg tablets under the trade names Aphrodyne, Dayto Himbin, Plain Prowess, Yocon and Yohimes.

Notes: Yohimbine is a pharmaceutical preparation derived from the bark of a tree called the Corynanthe yohimbine. It should not be confused with Yohimbe, which although is often the ground down bark of this tree, is not a pharmaceutical preparation and likely to contain???? a minute amount of Yohimbe.

Pharmacology: Synonyms: Aphrodine Hydrochloride: Chlorhydrate de Quebrachine; Corynine Hydrochloride. Chemical Name: Methyl 17 alpha hydroxy-yohimban-16alpha-carboxylate hydrochloride. Molecular Formula: C(21)H(26)N(2)O(3),HCL Molecular Weight: 390.9 CAS Registry: 146-48-5 (Yohimbine); 65-1 O (Yohimbine hydrochloride).

 
Return To Top
 
 

Response to Skeptics:

"Man who say it cannot be done should not interrupt man doing it."
- Chinese Proverb

 

DISCLAIMER:

This site does not provide medical or any other health care advice, diagnosis or treatment. The site and its services, including the information above, are for informational purposes only and are not a substitute for professional medical advice, examination, diagnosis or treatment. Always seek the advice of your physician or other qualified health professional before starting any new treatment or making any changes to existing treatment. Do not delay seeking or disregard medical advice based on information on this site. Medical information changes rapidly and while Anti-Aging-Today.org and its content providers make efforts to update the content on the site, some information may be out of date. No health information on Anti-Aging-Today.org , including information about herbal therapies and other dietary supplements, is regulated or evaluated by the Food and Drug Administration and therefore the information should not be used to diagnose, treat, cure or prevent any disease without the supervision of a medical doctor.

 
Copyright © 2017 Anti-Aging-Today.org All Rights Reserved.

Subscribe To Our
Free Anti-Aging Newsletter - Subscribe Here.
Anti-Aging Newsletter
For The Latest
News, Events &
Product Reviews
Anti-Aging-Today.org

I don't want to
achieve immortality
through my work;
I want to achieve
immortality through
not dying.

Woody Allen