The world's best-selling nootropic drug, Piracetam,
is purported to prevent and correct memory loss due to old age,
sharpening memory and improving clarity and attention to detail.
It is used to treat senile dementia and Down's syndrome. A derivative
of the amino acid GABA, Piracetam helps to restore levels of the
neurotransmitter Acetylcholine. It also increases the sensitivity
of muscuarinic receptors, which decreases with age. It brings
about important metabolic modifications in nerve cells, which
results in greater receptiveness and increased use of chemical
energy by these cells.
Piracetam's anti-aging benefits include treatment
and prevention of age-related mental decline, protection of the
brain against aging damage and environmental toxins, increased
potential life span, and improved alertness, awareness and short-to-medium-term
Pharmacology: Synonyms: C1-871; Pyrrolidone
Acetamide; UCB-6215. Chemical Name: 2-(2-Oxopyrrolidin-1-yl) acetamide.
Molecular Formula: C(6)H(10)N(2)(O)(2). Molecular Weight: 142.2
CAS Registry: 7491-74-9.
Side Effects and Contraindications: Side effects
may include nausea, dizziness and headaches. There are no known
contraindications, except for patients with hypersensitivity to
Piracetam. Patients with renal disorders should use Piracetam
Distribution: Piracetam is available most commonly
in 400mg, 600mg, 800mg and 1200mg tablets, and in an oral liquid
form. Trade name preparations include Avigilen, Axonyl, Braintop,
Cerebroforte TM, Cerebropan, Cerebrosteril TM, Cerebryl, Cerepar
N, Cetam, Ciclofalina, Cuxabrain TM, Enctrop, Flavis, Gabacet,
Genogris, Geram, Geratam, Memo Puren TM, Noodis, Nootrop, Nootropyl,
Normabrain, Norzetam, Novocetam, Pirabene, Piracebral TM, Piracetrop,
Psycoton and Sinapsan.
Notes: While some of the generic forms of Piracetam
may be acceptable, generic Piracetam may be a "hit or miss"
affair. There are now a growing number of Piracetam analogues,
including Oxiracetam, Aniracetam, Modiracetam, and Pramiracetam.
In all cases, with a comparison of mg product to kg body weight,
the analogues have been shown in clinical trials to be more potent.
Supplies of the analogues tend to be intermittent. Oxiracetam
is the industry standard in Europe and when new analogues are
developed, they are normally compared to Oxiracetam. In all cases,
however, the analogues are more expensive.
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