An important anti-aging and nootropic
drug, hydergine may help protect the brain from free radical damage
and oxygen starvation. Hydergine maintains the brain's optimal
metabolism of oxygen. Oxygen is a free radical scavenger and generator.
Free radicals cause age-associated damage, and at optimal levels,
oxygen will neutralize more free radicals than it generates. Hydergine
may also stimulate the growth of dendrite nerve fibers, which
may have a possible link to intelligence. Also, recent studies
suggest that hydergine may reduce Senescent Cell Antigen (SCA),
a destructive auto-antibody appearing more frequently in elderly
cells. SCA damages cells and finally destroys them.
Hydergine's anti-aging benefits may include
protection from free radical damage, especially to the brain and
the heart; protection from hypoxia and peroxidation; prevention
and treatment of strokes and other brain injuries; increased potential
life span; and improved and extended periods of mental workloads.
European studies on cats proved that hydergine-treated
cats survived severe diminished blood and oxygen supply for much
longer periods than non-hydergine-treated cats. Whereas, cats
in the control group suffered brain damage within five minutes,
cats treated with hydergine survived 45 minutes later with strong
brain wave patterns.
Pharmacology: Synonyms, Co-dergocrine Mesi Co-dergocrine
Methanesulphonate; Dihydroergotoxine Mesylate; Dihydroergotoxine
Methanesulphonate; Dihydrogenated Ergot Alkaloids; Ergoloid Mesylates
(USAN); hydrogenated Ergot Alkalids. CAS Registry: 11032-41-0
Side Effects and Contraindications: Mild side
effects including nausea, headache, flushing of the skin, dizziness,
and more rarely, vomiting, may occur with initial use. Stomach
upset may be more common with the tablet forms.
Hydergine is synergistic with other nootropics,
especially Piracetam and its analogues. Overall dosage may need
to be reduced.
Distribution: Hydergine is supplied in 1mg,
l.5mg, 3mg, 4.5mg, or 5mg tablets, and in sublingual liquid form
where it is possible to take 0.5mg doses at a time. There are
many generics on the world market. However, it is generally accepted
that the original manufacturers of hydergine, Sandoz, manufacture
the purest product.
Notes: It is still generally accepted that Sandoz,
the original producers of hydergine manufacture the highest purity
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